Recent Publications
論文・総説

2023年

  • Yokoyama, T., Yamagata, Y., Honna, S., Mizuno, S., Katagiri, S., Oi, R., Nogi, T., Hizukuri, Y.*, and Akiyama, Y.* (2023).
    S2P intramembrane protease RseP degrades small membrane proteins and suppresses the cytotoxicity of intrinsic toxin HokB. mBio, 14, e0108623.
    DOI : 10.1128/mbio.01086-23

2022年

  • Miyazaki, R., Ai, M.a, Tanaka, N. a, Suzuki, T., Dhomae, N., Tsukazaki, T., Akiyama, Y., and Mori, H.* (2022). aequally contributed
    Inner membrane YfgM–PpiD heterodimer acts as a functional unit that associates with the SecY/E/G translocon and promotes protein translocation. J. Biol. Chem., 298, 102572.
    DOI : 10.1016/j.jbc.2022.102572
  • Imaizumi, Y.a, Takanuki, K.a, Miyake, T.a, Takemoto, M., Hirata, K., Hirose, M., Oi, R., Kobayashi, T., Miyoshi, K., Aruga, R., Yokoyama, T., Katagiri, S., Matsuura, H., Iwasaki, K., Kato, K., Kaneko, M. K, Kato, Y., Tajiri, M., Akashi, S., Nureki, N., Hizukuri, Y.*, Akiyama, Y.*, and Nogi, T.* (2022). aequally contributed
    Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP. Sci. Adv., 8(34), eabp9011.
    DOI : 10.1126/sciadv.abp9011
  • Qiao, Z., Yokoyama, T., Yan, X., Beh, I., Shi, J., Basak, S., Akiyama, Y.*, and Gao, Y.* (2022).
    Cryo-EM structure of the entire FtsH-HflKC AAA protease complex. Cell Rep., 39, 110890.
    DOI : 10.1016/j.celrep.2022.110890

2021年

  • Miyazaki, R., Watanabe, T., Yoshitani, K., and Akiyama, Y.* (2021).
    Edge-strand of BepA interacts with immature LptD on the β-barrel assembly machine to direct it to on- and off-pathways. eLife, 10:e70541.
    DOI : 10.7554/eLife.70541
  • Yokoyama, T., Niinae, T., Tsumagari, K., Imami, K., Ishihama, Y., Hizukuri, Y.*, and Akiyama, Y.* (2021).
    The Escherichia coli S2P intramembrane protease RseP regulates ferric citrate uptake by cleaving the sigma factor regulator FecR. J. Biol. Chem., 296, 100673.
    DOI : 10.1016/j.jbc.2021.100673
  • Tamura-Sakaguchi, R., Aruga, R., Hirose, M., Ekimoto, T., Miyake, T., Hizukuri, Y., Oi, R., Kaneko, M. M., Kato, Y., Akiyama, Y., Ikeguchi, M., Iwasaki, K., and Nogi, T.* (2021).
    Moving toward generalizable NZ-1 labeling for 3D structure determination with optimized epitope tag insertion. Acta Crystallogr. D Struct. Biol., 77, 645-662.
    DOI : 10.1107/S2059798321002527

2020年

  • Miyazaki, R., Akiyama, Y., and Mori, H.* (2020).
    Fine interaction profiling of VemP and mechanisms responsible for its translocation-coupled arrest-cancelation. eLife, 9, e62623.
    DOI : 10.7554/eLife.62623
  • Miyake, T., Hizukuri, Y.*, and Akiyama, Y*. (2020). 
    Involvement of a membrane-bound amphiphilic helix in substrate discrimination and binding by an Escherichia coli S2P peptidase RseP. Front. Microbiol., 11, 607381.
    DOI : 10.3389/fmicb.2020.607381
  • Daimon, Y.a, Narita, S.a, Miyazaki, R., Hizukuri, Y., Mori, H., Tanaka, Y., Tsukazaki, T., and Akiyama, Y.* (2020). aequally contributed
    Reversible auto-inhibitory regulation of Escherichia coli metallopeptidase BepA for selective β-barrel protein degradation. Proc. Natl. Acad. Sci. USA. 117, (45) 27989-27996.
    DOI : 10.1073/pnas.2010301117