Yoshitani, K., Hizukuri, Y., and Akiyama, Y. (2019). An in vivo protease activity assay for investigating the functions of the Escherichia coli membrane protease HtpX. FEBS Lett., 593, 843-851.
Yoshitani, K.a, Ishii, E.a, Taniguchi, K., Sugimoto, H., Shiro, Y., Akiyama, Y., Kato, A., Utsumi, R., Eguchi, Y. (2019). aequally contributed Identification of an internal cavity in the PhoQ sensor domain for PhoQ activity and SafA-mediated control. Biosci. Biotechnol. Biochem., 11. 1-11.
Shahrizal, M., Daimon, Y., Tanaka, Y., Hayashi, Y., Nakayama, S., Iwaki, S., Narita, S.-i., Kamikubo, H., Akiyama, Y., Tsukazaki, T. (2019). Structural basis of the function of the β-barrel assembly-enhancing protease BepA. J. Mol. Biol., 431. 625-635.
2018年
Yura, T., Miyazaki, R., Fujiwara, K., Ito, K., Chiba, S., Mori, H., Akiyama, Y. (2018). Heat shock transcription factor σ32 defective in membrane transport can be suppressed by transposon insertion into the genes for a restriction enzyme subunit or a putative autotransporter in E. coli. Genes Genet. Syst., 93. 229-235.
Yamano, K., Wang, C., Sarraf, SA., Münch, C., Kikuchi, R., Noda, NN., Hizukuri, Y., Kanemaki, MT., Harper, W., Tanaka, K., Matsuda, N., Youle, RJ. (2018). Endosomal Rab cycles regulate Parkin-mediated mitophagy. eLife, 7, e31326.
Mori, H., Sakashita, S., Ito, J., Ishii, E., Akiyama, Y. (2018). Identification and characterization of a translation arrest motif in VemP by systematic mutational analysis. J. Biol. Chem., 293(8), 2915-2926.
Miyazaki, R., Myougo, N., Mori, H., Akiyama, Y. (2018). A photo-cross-linking approach to monitor folding and assembly of newly synthesized proteins in a living cell. J. Biol. Chem., 293(2), 677-686.
2017年
Daimon, Y., Iwama-Masui, C., Tanaka, Y., Shiota, T., Suzuki, T., Miyazaki, R., Sakurada, H., Lithgow, T., Dohmae, N., Mori, H., Tsukazaki, T., Narita, S.-i., Akiyama, Y. (2017). The tetratricopeptide repeat (TPR) domain of BepA is required for productive interaction with substrate proteins and the β-barrel assembly machinery (BAM) complex. Mol. Microbiol., 106(5), 760-776.
Furukawa, A., Yoshikaie, K., Mori, T., Mori, H., Morimoto, Y.V., Sugano, Y., Iwaki, S., Minamino, T., Sugita, Y., Tanaka, Y., Tsukazaki, T. (2017). Tunnel Formation Inferred from the I-Form Structures of the Proton-Driven Protein Secretion Motor SecDF. Cell Rep., 19(5), 895-901.
Akiyama, K., Hizukuri, Y., Akiyama, Y. (2017). Involvement of a conserved GFG motif region in substrate binding by RseP, an Escherichia coli S2P protease. Mol. Microbiol., 104(5), 737-751.
2016年
Miyazaki, R., Yura, T., Suzuki, T., Dohmae, N., Mori, H., and Akiyama, Y. (2016). A Novel SRP Recognition Sequence in the Homeostatic Control Region of Heat Shock Transcription Factor σ32. Scientific reports, 6, 24147.
2015年
Akiyama, K., Mizuno, S., Hizukuri, Y., Mori, H., Nogi, T., and Akiyama, Y. (2015). Roles of the membrane-reentrant β-hairpin-like loop of RseP protease in selective substrate cleavage. eLife, 4, e08928.
Ishii, E., Chiba, S., Hashimoto, N., Kojima, S., Homma, M., Ito, K., Akiyama Y., and Mori, H. (2015). Nascent chain-monitored remodeling of the Sec machinery for salinity adaptation of marine bacteria. Proceedings of the National Academy of Sciences, 112(40), E5513-E5522.
Daimon, Y., Narita, S.-i.* and Akiyama, Y.* (2015) Activation of TA system toxins suppresses lethality caused by the loss of σE in Escherichia coli. J. Bacteriol., 197, 2316-2324.
2014年
Kumazaki, K., Kishimoto, T., Furukawa, A., Mori, H., Tanaka, Y., Dohmae, N., Ishitani, R., Tsukazaki, T.*, and Nureki, O.* (2014) Crystal structure of Escherichia coli YidC, a membrane protein chaperone and insertase. Sci. Rep. 4, 7299.
Kumazaki, K., Chiba, S., Takemoto, M., Furukawa, A., Nishiyama, KI., Sugano, Y., Mori, T., Dohmae, N., Hirata, K., Nakada-Nakura, Y., Maturana, AD., Tanaka, Y., Mori, H., Sugita, Y., Arisaka, F., Ito, K., Ishitani, R., Tsukazaki, T., Nureki, O.(2014) Structural basis of Sec-independent membrane protein insertion by YidC. Nature.
Mio, M.*, Tsukazaki, T., Mori, H., Kawata, M., Moriya, T., Sasaki, Y., Ishitani, R., Ito, K., Nureki, O.* and Sato, C.* (2014) Conformational variation of the translocon enhancing chaperone SecDF. J. Struct. Funct. Genomics 15, 107-115
Arolas, JL., García-Castellanos, R., Goulas, T., Akiyama, Y., Gomis-Rüth, FX.,(2014) Expression and purification of integral membrane metallopeptidase HtpX. Protein Expr. Purif . 99C. 113-118.
Hizukuri, Y., Oda, T., Tabata, S., Tamura-Kawakami, K., Oi, R., Sato, M., Takagi, J., Akiyama, Y., Nogi, T.(2014) A structure-based model of substrate discrimination by a noncanonical PDZ tandem in the intramembrane-cleaving protease RseP. Structure 22, 326-336.
2013年
Lim, B., Miyazaki, R., Neher, S., Siegele, D. A., Ito, K., Walter, P., Akiyama, Y., Yura, T. and Gross, C. A., (2013) Heat shock transcription factor σ32 co-opts the signal recognition particle to regulate protein homeostasis in E. coli. PLoS Biol. 11, e1001735.
Narita, S., Masui, C., Suzuki, T., Dohmae, N., Akiyama, Y. (2013) Protease homolog BepA (YfgC) promotes assembly and degradation of β-barrel membrane proteins in Escherichia coli. Proc. Natl. Acad. Sci. USA. 110, E3612-3621.
2012年
Hizukuri, Y. and Akiyama, Y. (2012) PDZ domains of RseP are not essential for sequential cleavage of RseA or stress-induced σE activation in vivo. Mol. Microbiol. 86, 1232-1245.
Suno, R., Shimoyama, Abe, A., Shimodate, N., Watanabe, Y.-h., Akiyama, Y., and Yoshida, M. (2012) Conformational transition of the lid helix covering the protease active site is essential for the ATP-dependent protease activity of FtsH. FEBS Lett. 586, 3117-3121.
Xue, Y., Chowdhury, S., Liu, X., Akiyama, Y., Ellman, J. and Ha, Y. (2012) Conformational change in rhomboid protease GlpG induced by inhibitor binding to its S’ subsites. Biochemistry 51, 3723-3731.
2011年
Ito, K., Chadani, Y., Nakamori, K., Chiba, S., Akiyama, Y., and Abo, T. (2011) Nascentome analysis uncovers futile protein synthesis in Escherichia coli. PLoS ONE 6, e28413.
Saito, A., Hizukuri, Y., Matsuo, E. -i., Chiba, S., Mori, H., Nishimura, O., Ito, K. and Akiyama, Y. (2011) Post-liberation cleavage of signal peptides is catalyzed by the site-2 protease (S2P) in bacteria. Proc. Natl. Acad. Sci. USA. 108, 13740-13745.
Tsukazaki, T.a), Mori, H.a), Echizen, Y., Ishitani, R., Fukai, S., Tanaka, T., Perederina, A., Vassylyev, D. G., Kohno, T., Maturana, A. D., Ito, K. and Nureki, O. (2011) Structure and function of a membrane component SecDF that enhances protein export. Nature 474, 235-238. a) equally contributed.
Chiba, S., Kanamori, T., Ueda, T., Akiyama, Y., Pogliano, K. and Ito, K. (2011) Recruitment of a species-specific translational arrest module to monitor different cellular processes. Proc. Natl. Acad. Sci. USA. 108, 6073-6078.
